| Title:
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PROTEIN QUALITY CONTROL IN NEURODEGENERATIVE DISEASES
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| By: |
Richard I. Morimoto (Editor), Yves Christen (Editor) |
| Format: |
Hardback |
| List price:
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£139.99 |
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| ISBN 10: |
3642279279 |
| ISBN 13: |
9783642279270 |
| Publisher: |
SPRINGER-VERLAG BERLIN AND HEIDELBERG GMBH & CO. KG |
| Pub. date: |
12 December, 2012 |
| Edition: |
2013 ed. |
| Series: |
Research and Perspectives in Alzheimer's Disease |
| Pages: |
136 |
| Description: |
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. This title deals with this topic. |
| Synopsis: |
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins. The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease associated misfolded proteins. Substantial evidence supports the hypothesis that the expression of damaged proteins initiates a cascade of molecular events that leads to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease, and other diseases of protein conformation. |
| Illustrations: |
10 Tables, black and white; XII, 136 p. |
| Publication: |
Germany |
| Imprint: |
Springer-Verlag Berlin and Heidelberg GmbH & Co. K |
| Returns: |
Returnable |