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Item Details
| Title:
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INTEGRINS AND ICAM-1 IN IMMUNE RESPONSES
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| Volume: |
v. 50 |
| By: |
H. Renz, N. Hogg (Editor) |
| Format: |
Hardback |
| List price:
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£76.10 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
380555429X |
| ISBN 13: |
9783805554299 |
| Publisher: |
S KARGER AG |
| Pub. date: |
1 October, 1991 |
| Series: |
Chemical Immunology & Allergy 50 |
| Pages: |
168 |
| Description: |
An overview of the structure and function of a number of integrins and of intercellular adhesion molecule-1(ICAM-1). Topics covered include the regulation of leukocyte integrin function, the role of VLA integrins in lymphocyte migration and recognition, and common integrin recognition mechanisms. |
| Synopsis: |
The regulation of cell adhesion is a prerequisite for establishing and maintaining a normal host defence system. One of the main classes of molecules mediating cellular adhesive interactions is the integrin, a broadly distributed family of transmembrane receptors. This book offers an overview of the structure and function of a number of integrins and also of intercellular adhesion molecule-1(ICAM-1). Topics covered include the regulation of leukocyte integrin function, the role of VLA integrins in lymphocyte migration and recognition, common and ligand-specific integrin recognition mechanisms, and the role of integrin alpha-481 in lymphocyte-endothelial cell interactions. The second part of the book highlights the importance of ICAM-1, an immunoglobulin and ligand for the leukocyte integrin LFA-1. Its role in inflammation and tumour development is discussed, as well as its relevance as a receptor for rhinovirus and plasmodium falciparum-infected erythrocytes. |
| Illustrations: |
21, 21 fig., 11 tab. |
| Publication: |
Switzerland |
| Imprint: |
S Karger AG |
| Returns: |
Non-returnable |
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