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Item Details
Title: DEVELOPMENT AND CLINICAL PROGRESS OF DNA VACCINES
LANGEN, OCTOBER 1999
Volume: Paul-Ehrlich-institut, Langen, October 1999
By: F. Brown (Editor), K. Cichutek (Editor), J.S. Robertson (Editor)
Format: Paperback

List price: £82.36


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 380557102X
ISBN 13: 9783805571029
Publisher: S KARGER AG
Pub. date: 1 January, 2000
Series: Developments in Biologicals v. 104
Pages: 214
Description: DNA vaccines have progressed rapidly from the conceptual stage to the stage of clinical trials. This volume contains the proceedings of a meeting devoted to the developments in DNA vaccines, from laboratory studies to clinical trials. Written by leaders in the field, it focuses on the state of DNA vaccines in humans and other large animals.
Synopsis: DNA vaccines have progressed rapidly from the conceptual stage to the stage of clinical trials. While studies in small laboratory animals have shown great promise, initial reports from human studies were less encouraging. Progress is being made, however, documented by the papers presented here. This volume contains the proceedings of a meeting devoted to the latest developments in DNA vaccines, from laboratory studies to clinical trials. The papers, written by leaders in the field, focus on the current state of DNA vaccines in humans and other large animals. The bulk of the studies involve DNA vaccines against HIV/SIV. Other promising trials make use of DNA vaccines against malaria and hepatitis B. The papers inform the reader about the immune basis of this form of vaccination and about approaches being developed to increase the efficacy of DNA vaccines in humans. These include the co-administration of cytokines, prime-boost strategies, optimising codon usage or the use of CpG motifs. An excellent up-to-the-minute account, this volume should be read by anyone in academia or in industry involved in DNA vaccination.The book will also be of great interest to clinicians involved in trials and those in the regulatory area.
Illustrations: 40, 40 fig., 22 tab.
Publication: Switzerland
Imprint: S Karger AG
Returns: Non-returnable
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ADVANCING SCIENCE AND ELIMINATION OF THE USE OF LABORATORY ANIMALS FOR DEVELOPMENT AND CONTROL OF VACCINES AND HORMONES (PB)
ALTERNATIVES TO ANIMALS IN THE DEVELOPMENT AND CONTROL OF BIOLOGICAL PRODUCTS FOR HUMAN AND VETERINARY USE (PB)
ANIMAL SERA, ANIMAL SERA DERIVATIVES AND SUBSTITUTES USED IN THE MANUFACTURE OF PHARMACEUTICALS (PB)
BIOLOGICAL CHARACTERIZATION AND ASSAY OF CYTOKINES AND GROWTH FACTORS (PB)
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CHARACTERIZATION OF BIOTECHNOLOGY PHARMACEUTICAL PRODUCTS (PB)
DEVELOPMENT OF SPECIFICATIONS FOR BIOTECHNOLOGY PHARMACEUTICAL PRODUCTS (PB)
IMMUNOGENICITY OF THERAPEUTIC BIOLOGICAL PRODUCTS (PB)
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LABORATORY CORRELATES OF IMMUNITY TO INFLUENZA, A REASSESSMENT (PB)
MODULATION OF THE IMMUNE RESPONSE TO VACCINE ANTIGENS (PB)
NEW APPROACHES TO STABILISATION OF VACCINES POTENCY (PB)
NOVEL INFECTIOUS AGENTS AND THE CENTRAL NERVOUS SYSTEM (HB)
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PERTUSSIS VACCINE TRIALS (PB)
PHYSICO-CHEMICAL PROCEDURES FOR THE CHARACTERIZATION OF VACCINES (PB)
PRECLINICAL AND CLINICAL DEVELOPMENT OF NEW VACCINES SYMPOSIUM (PB)
PROCESS VALIDATION FOR MANUFACTURING OF BIOLOGICS AND BIOTECHNOLOGY PRODUCTS (PB)
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VACCINES FOR OIE LIST A AND EMERGING ANIMAL DISEASES (PB)
VIRAL SAFETY AND EVALUATION OF VIRAL CLEARANCE FROM BIOPHARMACEUTICAL PRODUCTS (PB)

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