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Item Details
Title: LABORATORY CORRELATES OF IMMUNITY TO INFLUENZA, A REASSESSMENT
INFORMAL SCIENTIFIC WORKSHOP, BERGEN, MAY 2002
By: F. Brown (Editor), L. R. Haaheim (Editor), J. M. Wood (Editor)
Format: Paperback

List price: £84.20


We currently do not stock this item, please contact the publisher directly for further information.

ISBN 10: 3805577354
ISBN 13: 9783805577359
Publisher: S KARGER AG
Pub. date: 4 February, 2004
Series: Developments in Biologicals v. 115
Pages: 164
Description: For some years, it has been a rule of thumb that antibody to influenza haemagglutinin, induced by natural infection or vaccination, is a useful marker of immunity to influenza. This work aims to review the methods for assessing immune responses, their advantages and disadvantages and give information on immune responses to various vaccine types.
Synopsis: For some 30 years it has been a rule of thumb that antibody to influenza haemagglutinin, induced by natural infection or vaccination, is a universal and useful marker of immunity to influenza. It now seems important to re-examine this hypothesis. Knowledge of the mechanisms of acquired influenza immunity and correlations with measurable laboratory parameters is clearly of importance in understanding influenza epidemiology and vaccine-induced immunity. While immunity is certainly multi-factorial, involving both B and T cell responses, any comprehensive assessment is complicated by the capacity of the virus to undergo extensive and frequent antigenic variation. The aim of this workshop was to review the methods available for assessing immune responses and their advantages and disadvantages; to present information on immune responses to the various vaccine types and attempt to draw possible conclusions on their value in assessing protective immunity; to address the question of standardization and validation of assays and the appropriate use of reference materials; to identify appropriate themes for international collaborative studies.
Illustrations: 14, 14 fig., 19 tab.
Publication: Switzerland
Imprint: S Karger AG
Returns: Non-returnable
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