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Item Details
| Title:
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DESIGN OF ENZYME INHIBITORS AS DRUGS, VOLUME 2
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| By: |
Merton Sandler (Editor), H. John Smith (Editor) |
| Format: |
Hardback |
| List price:
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£257.50 |
| Our price: |
£257.50 |
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| ISBN 10: |
0192621343 |
| ISBN 13: |
9780192621344 |
| Availability: |
Usually dispatched within 1-3 weeks.
 Delivery
rates
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| Stock: |
Currently 0 available |
| Publisher: |
OXFORD UNIVERSITY PRESS |
| Pub. date: |
21 April, 1994 |
| Pages: |
848 |
| Description: |
This volume is an authoritative text on the latest developments in the design of enzyme inhibitors as potent drugs for the treatment of disease and infection. This type of drug exerts its action by modifying a particular body function or combating an infection by blocking the action of a specific enzyme. The text describes the development of such drugs, all the way through from their inception to their satisfactory marketing, a process full of potential difficultiesand requiring the skills of an interdisciplinary team of chemists, biochemists, pharmacologists, and clinicians. |
| Synopsis: |
A high proportion of drugs currently coming to market exert their action in the body by inhibition of a target enzyme involved in a particular body function or in a bacterium, protozoon, or virus causing an infection. This book extends the previous volume in providing a comprehensive coverage of more recently recognised target enzymes and their known inhibitors, and within this framework of knowledge demonstrates how the drug designer uses all available information to develop a specific therapeutic agent. Drug design is an interdisciplinary art and the text illustrates the pathway followed from the initial design concept and synthesis of an inhibitor through its in vitro and in vivo assessments to clinical trial, a process involving chemists, biochemists, pharmacologies, and clinicians. |
| Illustrations: |
halftones, numerous line drawings, tables |
| Publication: |
UK |
| Imprint: |
Oxford University Press |
| Returns: |
Returnable |
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