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Item Details
| Title:
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MOLECULAR DRUG PROPERTIES
MEASUREMENT AND PREDICTION |
| By: |
Raimund Mannhold (Editor), Raimund Mannhold, Hugo Kubinyi |
| Format: |
Hardback |
| List price:
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£214.95 |
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We currently do not stock this item, please contact the publisher directly for
further information.
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| ISBN 10: |
3527317554 |
| ISBN 13: |
9783527317554 |
| Publisher: |
WILEY-VCH VERLAG GMBH |
| Pub. date: |
24 October, 2007 |
| Series: |
Methods and Principles in Medicinal Chemistry |
| Pages: |
502 |
| Description: |
A unique handbook that shows the best and quickest way to estimate those molecular properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity, pKa, solubility, permeation and conformation. |
| Synopsis: |
This first systematic overview for more than a decade is tailor-made for the medicinal chemist. All the chapters are written by experienced drug developers and include practical examples from real drug candidates. Following an introduction to global drug properties and their impact on drug research, screening and combinatorial chemistry libraries, this handbook demonstrates the best and fastest way to estimate those properties most relevant for the efficiency and pharmacokinetic performance of a drug molecule: lipophilicity,solubility, electronic properties and conformation. |
| Illustrations: |
Illustrations (some col.) |
| Publication: |
Germany |
| Imprint: |
Wiley-VCH Verlag GmbH |
| Returns: |
Returnable |
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