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Item Details
Title: NATURAL PRODUCTS IN MEDICINAL CHEMISTRY
By: Stephen Hanessian (Editor), Raimund Mannhold, Hugo Kubinyi
Format: Hardback

List price: £144.95
Our price: £119.58
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ISBN 10: 3527332189
ISBN 13: 9783527332182
Availability: Usually dispatched within 1-3 weeks.
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Publisher: WILEY-VCH VERLAG GMBH
Pub. date: 12 February, 2014
Series: Methods and Principles in Medicinal Chemistry
Pages: 652
Description: Well-documented case studies from recent drug development projects highlight the current and future importance of natural products as drug precursors, including much valuable practical knowledge for medicinal chemists working in or entering the field.
Synopsis: The inspiration provided by biologically active natural products to conceive of hybrids, congeners, analogs and unnatural variants is discussed by experts in the field in 16 highly informative chapters. Using well-documented studies over the past decade, this timely monograph demonstrates the current importance and future potential of natural products as starting points for the development of new drugs with improved properties over their progenitors. The examples are chosen so as to represent a wide range of natural products with therapeutic relevance among others, as anticancer agents, antimicrobials, antifungals, antisense nucleosides, antidiabetics, and analgesics. From the content: * Part I: Natural Products as Sources of Potential Drugs and Systematic Compound Collections * Part II: From Marketed Drugs to Designed Analogs and Clinical Candidates * Part III: Natural Products as an Incentive for Enabling Technologies * Part IV: Natural Products as Pharmacological Tools * Part V: Nature: The Provider, the Enticer, and the Healer
Illustrations: Illustrations
Publication: Germany
Imprint: Wiley-VCH Verlag GmbH
Returns: Returnable
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